Jul 5, 2017 The clinical differential diagnoses included bullous pemphigoid, The diagnosis of bullous diabeticorum is a diagnosis of exclusion, and
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Potential causes include infections and drugs such as dipeptidyl peptidase-4 soon as possible with reference to the Parkland formula.4; Bullous diabeticorum. May 21, 2016 Table 1: Different clinical manifestations of BP and differential diagnoses. Clinical Bullosis diabeticorum. Pemphigoid nodularis forms of the disease makes the diagnosis of bullous pemphigoid difficult. The diagn cations have been identified as causes of EN (29).
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Lesions appear rapidly, primarily in an acral distribution in areas of otherwise normal-appearing skin, and range from a few centimeters to very large. The differential diagnosis includes friction bullae, bullae due to burns or edema, bullous fixed drug reaction, bullous pemphigoid, and epidermolysis bullosa acquisita.{ref3} The differential diagnosis must be made with epidermolysis bullosa, pemphigus, We report a case of bullosis diabeticorum with blisters confined to the lower legs and feet. The diagnosis of BD entails punch biopsies and subsequent histopathologic examination . The histologic features of bullosis diabeticorum are not very specific. Histology typically reveals a noninflammatory blister with separation in an intraepidermal or subepidermal location. Anchoring fibrils and hemidesmosomes tend to be decreased. Clinically important is the association of bullosis diabeticorum with diabetic retinopathy, nephropathy and polyneuropathy.
2019-12-06
Key words: diabetic bullae, bullosis diabeticorum, diabetes. Introduction Bullosis diabeticorum, or diabetic bulla, is rare and usually occurs in long-standing type 1 DM but can also occur in poorly controlled type 2 DM. 2-4 However, as there is no direct correlation with glycemic control, it also rarely occurs in prediabetes and undiagnosed diabetes. 5 The lesion occurs spontaneously and abruptly (without any antecedent trauma) as painless, noninflammatory, and 2016-07-11 About 0.5% of diabetics develop diabetic bullae or bullosis diabeticorum, a distinct diabetic marker.
Diagnosis confirmation –Bullae, clear or hemorrhagic, associated with neuropathy (lack of sensation) over pressure points on the feet. Can appear rapidly with minimal or unidentified friction/pressure.
For differential diagnosis, the presence of Raynaud phenomenon, plaque-type morphea, bullous morphea,. 978 Buschke, scleredema diabeticorum is.
Bullosis Diabeticorum. J Gen Intern Med. 2017 Feb;32(2):220.doi: 10.1007/s11606-016-3802-3. Epub 2016 Jul 11. Authors.
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The bullae occur more frequently in adult men with long standing diabetes and neuropathy. The pathogenesis of diabetic bullae is unclear. These painless bullae may be the first presentation of diabetes, appearing suddenly, commonly on lower limbs. We present a case of bullosis diabeticorum. It is a rare disorder, probably underdiagnosed, associated with long-term diabetes mellitus.
Affiliations. 1Department of Internal Medicine, Carolinas Medical Center, 1000 Blythe Blvd Suite 507, Charlotte, NC, 28203, USA.
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We present a case of bullosis diabeticorum. It is a rare disorder, probably underdiagnosed, associated with long-term diabetes mellitus. Its etiology remains unclear.
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Diabetic bullae, also known as bullosis diabeticorum, are blister-like lesions that occur spontaneously on the feet and hands of diabetic patients. Although rare, diabetic bullae are a distinct marker for diabetes. Diabetic bullae are more common in men than women; They are prevalent between the ages of 17 and 84 years.
6 This was first reported in 1930 and there is a male preponderance. 6 It was reported in nearly 2% of the diabetic population in a study done in India. 7 They are common in the hands and the feet with the The diagnosis of BD entails punch biopsies and subsequent histopathologic examination .